Glycation


The phenomenon of glycation

Also called “the Maillard reaction” , the phenomenon of glycation is little known, although at the heart of aging mechanisms. It is a chemical reaction resulting from the attachment of sugars to proteins. These can modify their structure by freezing them, which can then lead to a loss of their function . This step is commonly referred to as protein caramelization .

To better understand and illustrate this phenomenon, we can take the example of toast. Under the heat of the toaster, the proteins present in the flour bind to the sugar molecules in the Maillard reaction process. It is this reaction that gives the crunchy texture of toasted bread!

These glycation products are called AGEs (Advanced Glycation End-products). They can form naturally in our body, but particularly in the event of a significant rise in blood sugar and the vast majority through food .

The problem with AGEs is that once produced, a return to the initial state is impossible ! They come from an irreversible chemical reaction and the only way to eliminate them is to evacuate them in the urine . AGEs therefore accumulate in the body by modifying and preventing our cellular receptors from functioning properly . These AGEs are the cause of many signs of aging and multiple complications of chronic diseases .

Glycation, a major factor in aging

The causes of aging are categorized into two: intrinsic factors such as genetic and hormonal factors , and extrinsic factors directly related to our habits (diet, exposure to the sun, stress, pollution, etc.).

Glycation is central to both of these factors . Exposure to UVs, genetic and hormonal factors therefore aggravate this phenomenon.

From an aesthetic point of view, AGEs are responsible for wrinkles , fine lines and dark spots . By freezing our collagen proteins, glycation will make the skin less supple and stiffer . It will then lose its natural elasticity . Unfortunately, collagen proteins are present throughout the body and the skin is not the only organ affected.

The brain , the lens and the vessels are also. This has the effect of increasing the development of cardiovascular diseases , causing complications of diabetes and neurodegenerative diseases .

How to fight against glycation?

1) Food

It is essential to pay particular attention to your diet to fight against the phenomenon of glycation. Indeed, certain foods and cooking methods provide by-products and promote the Maillard reaction, so they must be limited .

Baking and barbecuing should be avoided . Browned , au gratin and caramelized foods can multiply the amount of glycation products by 10 !

All foods with a high glycemic index such as sweet desserts, jams, pizzas, potatoes, cola or malt-based drinks, grilled meats, also promote this phenomenon.

To fight against glycation, steaming and low temperature cooking is preferred.

Certain foods would also have an anti-glycation action such as blueberries, grapes, onions, leeks, garlic, cabbage and certain spices such as rosemary, turmeric, cinnamon, thyme… .

2) Absolute D-Glyc from D-LAB NUTRICOSMETICS

Absolu D-Glyc is an innovative formula that acts against the harmful effects of sugars on proteins, the famous “protein caramelization”. Absolute D-Glyc provides two molecules, L-Carnosine and Carcinine . which are molecules made by our body from amino acids, but which become rare as we age. This formula has a double action against glycation : it reduces it and de-glycates the proteins altered by sugar .

De-glycation is the release of glycated proteins, restoring their natural integrity. Carcinine acts on glycated proteins to free them from sugar, they then resume their essential structural role in the skin.

By reducing glycation, Absolu D-Glyc visibly reduces the signs of aging. 

3) The Absolu Hyaluronique + D-GLYC combination to feel good about your age

With age , cell regeneration is slowed down and the skin loses its ability to retain water. The combination of Absolute Hyaluronic and Absolute D-Glyc supports, improves and preserves the health of your skin by deeply rehydrating it. This Pro-Aging Duo accompanies the skin by taking into account the biological phenomena of aging occurring at the cellular and molecular level. It then becomes smoother , plumper and firmer .

4) Sports

In addition to the advice given above, the practice of a regular sports activity also intervenes in the fight against glycation and is always beneficial for the body !

Indeed, sport for 150 minutes (minimum) per week reduces the level of glycated hemoglobin.

Your best pro-aging allies are therefore a quality diet , Absolute D-Glyc and regular physical activity !

Absolute d-GLYC

Anti-Aging Precursor & Glycation

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Absolute HYALURONIC

Deep rehydration

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COLLAGEN Absolute

Wrinkles & Firmness

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